Presentations
Presentations
Discovery, Expression, and Characterization of Neutralizing Picobodies against SARS-CoV2
Antibody Engineering and Therapeutics, 2021
At 4-6 KD, “picobodies” represent the smallest known Ig-derived binding moiety capable of high affinity interactions with target proteins.
Presentations
Chicken Heavy Chain only antibodies to SARS-CoV2
Antibody Engineering and Therapeutics, 2021
Single domain antibodies are found naturally in camelids and sharks, and humanized versions have been engineered.
Presentations
Antibody Discovery Powered By OmniAb
Antibody Engineering and Therapeutics, 2021
The OmniAb platform couples cutting edge screening and data mining technologies with highly validated antibody generation systems.
Publications
Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for...
MAbs, 2021
Bispecific antibodies are an important and growing segment in antibody therapeutics, particularly in the immuno-oncology space. Manufacturing of a bispecific antibody with…
Presentations
xPloration®: High Throughput B Cell Profiling for Antibody Discovery from OmniAb Immune Repertoires
2020
The success of a therapeutic antibody is directly related to its biological activity, which is a function of the epitope to which it binds on the target, its specificity, its affinity, and its sequence…
Publications
Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing
2020
The humanization of animal model immune systems by genetic engineering has shown great promise for antibody discovery, tolerance studies and for the evaluation of vaccines…
Publications
Expression of human lambda expands the repertoire of OmniChickens
PLOS ONE, 2020
Most of the approved monoclonal antibodies used in the clinic were initially discovered in mice. However, many targets of therapeutic interest are highly conserved…
Presentations
OmniTaur™: Ultralong CDR3 cow antibodies for challenging targets
2020
Bovine antibodies are unusual in having exceptionally long heavy chain CDR3 regions, with an average length of 25 amino acids, and an ‘ultralong’ subset that can reach >70 amino acids in length…
Presentations
Benchmarking discovery-stage antibodies from OmniChicken (against clinical-stage antibodies from other sources)
2019
Presentation by Bill Harriman and Shelley Izquierdo
Presentations
OmniFlic and OmniClic: Transgenic Rat and Chicken Platforms for Human Bispecific Antibody Discovery
2019
Presentation by Christel Iffland and Kathryn Ching