Scientific Publications

There is an ever-increasing need of monoclonal antibodies (mAbs) for biomedical applications and fully human binders are particularly desirable due ...

The analysis of secreted antibody from large and diverse populations of B cells in parallel at the clonal level can ...

The ability of monoclonal antibodies (mAbs) to target specific antigens with high precision has led to an increasing demand to ...

Since the discovery of antibody-producing B cells in chickens six decades ago, chickens have been a model for B-cell development ...

The CRISPR/Cas9 system has been applied in a large number of animal and plant species for genome editing. In chickens, ...

Cre recombinase has been extensively used for genome engineering in transgenic mice yet its use in other species has been ...

During the past decade, modifications to the chicken genome have evolved from random insertions of small transgenes using viral vectors ...

Chicken immune responses to human proteins are often more robust than rodent responses because of the phylogenetic relationship between the ...

Fully human antibodies from transgenic animals account for an increasing number of new therapeutics. After immunization, diverse human monoclonal antibodies ...

Human antibody expression in transgenic rodents has been significantly improved by the integration of large chimeric DNA constructs linking human ...

Expression of human antibody repertoires in transgenic animals has been accomplished by introducing large human Ig loci into mice and, ...

Gene targeting by homologous recombination or by sequence-specific nucleases allows the precise modification of genomes and genes to elucidate their ...