Scientific Publications

Transgenic animal platforms for the discovery of human monoclonal antibodies have been developed in mice, rats, rabbits and cows. The ...

An important characteristic of chickens is that the antibody repertoire is based on a single framework, with diversity found mainly ...

We created a novel transgenic rat that expresses human antibodies comprising a diverse repertoire of heavy chains with a single ...

Identifying monoclonal antibodies that block human voltage-gated ion channels (VGICs) is a challenging endeavor exacerbated by difficulties in producing recombinant ...

Oligomannose-type glycans are among the major targets on the gp120 component of the HIV envelope protein (Env) for broadly neutralizing ...

Raising functional antibodies against G protein-coupled receptors (GPCRs) is challenging due to their low density expression, instability in the absence ...

There is an ever-increasing need of monoclonal antibodies (mAbs) for biomedical applications and fully human binders are particularly desirable due ...

The analysis of secreted antibody from large and diverse populations of B cells in parallel at the clonal level can ...

The ability of monoclonal antibodies (mAbs) to target specific antigens with high precision has led to an increasing demand to ...

Since the discovery of antibody-producing B cells in chickens six decades ago, chickens have been a model for B-cell development ...

The CRISPR/Cas9 system has been applied in a large number of animal and plant species for genome editing. In chickens, ...

Cre recombinase has been extensively used for genome engineering in transgenic mice yet its use in other species has been ...