Scientific Publications
Publications
Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.
Publications
PLOS ONE, 2013
Transgenic chickens expressing human sequence antibodies would be a powerful tool to access human targets and epitopes that have been ...
Publications
High-Affinity IgG Antibodies Develop Naturally in Ig-Knockout Rats Carrying Germline Human IgH/Igk/Igl Loci...
Publications
J Immunol., 2013
Mice transgenic for human Ig loci are an invaluable resource for the production of human Abs. However, such mice often ...
Publications
Characterization of immunoglobulin heavy chain knockout rats
Publications
Eur. J. Immunol., 2010
The rat is a species frequently used in immunological studies but, until now, there were no models with introduced gene-specific ...
Publications
Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
Publications
Science, 2009
The toolbox of rat genetics currently lacks the ability to introduce site-directed, heritable mutations into the genome to create knockout ...