Presentations

Discovery, Expression, and Characterization of Neutralizing Picobodies against SARS-CoV2

Antibody Engineering and Therapeutics, 2021

At 4-6 KD, “picobodies” represent the smallest known Ig-derived binding moiety capable of high affinity interactions with target proteins.

Presentations

Chicken Heavy Chain only antibodies to SARS-CoV2

Antibody Engineering and Therapeutics, 2021

Single domain antibodies are found naturally in camelids and sharks, and humanized versions have been engineered.

Presentations

Antibody Discovery Powered By OmniAb

Antibody Engineering and Therapeutics, 2021

The OmniAb platform couples cutting edge screening and data mining technologies with highly validated antibody generation systems.

Publications

Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for...

MAbs, 2021

Bispecific antibodies are an important and growing segment in antibody therapeutics, particularly in the immuno-oncology space. Manufacturing of a bispecific antibody with…

Presentations

xPloration®: High Throughput B Cell Profiling for Antibody Discovery from OmniAb Immune Repertoires

2020

The success of a therapeutic antibody is directly related to its biological activity, which is a function of the epitope to which it binds on the target, its specificity, its affinity, and its sequence…

Publications

Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

2020

The humanization of animal model immune systems by genetic engineering has shown great promise for antibody discovery, tolerance studies and for the evaluation of vaccines…

Publications

Expression of human lambda expands the repertoire of OmniChickens

PLOS ONE, 2020

Most of the approved monoclonal antibodies used in the clinic were initially discovered in mice. However, many targets of therapeutic interest are highly conserved…

Presentations

OmniTaur™: Ultralong CDR3 cow antibodies for challenging targets

2020

Bovine antibodies are unusual in having exceptionally long heavy chain CDR3 regions, with an average length of 25 amino acids, and an ‘ultralong’ subset that can reach >70 amino acids in length…

Presentations

Antigen Design Technology

2019

Presentation by John S. Burg

Presentations
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