Why OmniAb?
A unique offering to address critical industry needs
Your therapeutic development relies on discovery of high-quality antibody leads. OmniAb’s proprietary and validated transgenic animals. OmniRat®, OmniMouse®, and OmniChicken®, are each capable of generating high quality fully human antibodies, naturally optimized through in vivo affinity maturation. OmniFlic® and OmniClic® are fixed or common light-chain rats and chickens, respectively, designed to facilitate the discovery of bispecific antibodies. OmnidAb® is an in vivo platform for the discovery of single domain antibodies based upon a human VH scaffold that affinity matures in a chicken host. The OmniUltra™ platform, generates naturally optimized human immune antibody repertoires featuring cow-inspired ultralong CDRH3 domains.
Flexible options for transgenic animal species and discovery processes are key to success
Because each human Ig-transgenic host animal provides a distinct immune response profile, the availability of multiple species offers more options to find the ideal therapeutic candidate.
Our project teams work closely with partners to customize and optimize the discovery process for each campaign. You can choose between your internal processes, OmniAb proprietary screening technologies, or methods offered by CROs, such as hybridoma, display libraries, B-cell cloning, and next-generation sequencing.
Access a full range of transgenic animals for your discovery campaigns:
OmniMouse delivers fully human antibodies using standard mouse-based protocols.
OmniChicken and OmniClic® are optimized for human antibody research.
A human VH domain benefiting from being generated in a chicken host. Discover OmnidAb®.
