Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.
Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.
Strategies to Obtain Diverse and Specific Human Monoclonal Antibodies From Transgenic Animals.
Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies.
Human Antibody Production in Transgenic Animals.
Transgenic Animals Derived by DNA Microinjection.
Human antibody expression in transgenic rats: Comparison of chimeric IgH loci with human VH, D and JH but bearing different rat C-gene regions.
High-Affinity IgG Antibodies Develop Naturally in Ig-Knockout Rats Carrying Germline Human IgH/Igk/Igl Loci Bearing the Rat CH Region.
Characterization of immunoglobulin heavy chain knockout rats.
Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases.