Research Associate

The Research Associate works under the direction of a scientist supporting Ligand’s OmniAb Technology with responsibilities in multiple research areas including: generating and characterizing new strains of OmniChickens; conducting OmniAb antibody discovery campaigns for internal and partner programs; preparing custom protein reagents for immunization and screening; antibody engineering and optimization of lead molecules for further development.

The OmniAb group at Ligand consists of dynamic and innovative scientists that employ a variety of novel platforms to support our partners in discovering the best antibodies possible for their therapeutic applications.  At the core of OmniAb is the ability to engineer animals to generate affinity matured human sequence antibodies for use in conventional and novel formats.  We leverage our proprietary animals with state-of-the-art technology in antigen design, immunization methods and high-throughput single B cell screening to facilitate discovery of best-in-class antibodies.   We are looking for accomplished team players who are enthusiastic to contribute to the technological frontier of antibody discovery, and passionate in their desire to collaborate with partners to develop next generation therapeutics.  See for more details about the exciting science being performed at Ligand.

This is an unique opportunity to gain exposure to many aspects of antibody discovery. We strongly urge candidates whose future plans might include graduate school, to apply.

About Ligand    •    Ligand is a biopharmaceutical company focused on developing or acquiring technologies that help pharmaceutical companies discover and develop medicines. Ligand employs research technologies such as antibody discovery technologies, ion channel discovery technology, Pseudomonas fluorescens protein expression technology, formulation science and liver targeted pro-drug technologies to assist companies in their work toward securing prescription drug and biologic approvals. We have contributed novel research and technologies for approved medicines that treat cancer, osteoporosis, fungal infections and postpartum depression, among others. 

Essential Role Responsibilities

Depending on the research area, the tasks you will be performing are:

  • Conduct PCR, molecular cloning and site-directed mutagenesis
  • Perform transfections and propagate mammalian tissue culture cell lines
  • Maintain an accurate electronic lab notebook and present data at group meetings
  • Prepare experimental data reports for partner and internal antibody discovery programs

Non-essential Role Responsibilities Include

  • Support and participate in scientific conferences
  • Back-up to support other programs
  • Other duties as required

Experience and skills

  • B.Sc.
  • Experience in one of the following areas: primary cell culture (ES and IPS cells), molecular biology, immunology, structural biology and biochemistry. 
  • Well-developed communication, record keeping, organizational skills, and the ability to work in a team environment 


The company offers competitive benefits including medical, dental, vision, Short/Long term disability and life insurance, as well as 401(k) match, Stock Options, Bonus, and paid time leave

Additional Information

All new hires are required to go through a background and reference check
Ligand is an EEO/AA/Disability/Vets employer
Must be legally authorized to work in the US without sponsorship
Ligand celebrates the diversity of life and welcomes all individuals to apply No agencies or phone calls please 

Apply Here

« Back to Careers